April 2026 Question
CHEST SEEK® Challenge: In addition to supportive treatment, empiric antibiotics while cultures are obtained and followed, and corticosteroids, which administration of treatment should be included in initial management?

A patient with relapsed diffuse large B-cell lymphoma has been admitted to the ICU 4 days after receiving chimeric antigen receptor (CAR) T-cell therapy. In the past 24 hours, the patient has developed fever followed by hypotension and hypoxemic respiratory failure.

 

 

This question is found in the print edition, CHEST SEEK® Critical Care Medicine: 32nd Edition, and in the CHEST SEEK Library.

The SEEK Challenge question is updated monthly. Check back in May for next month's question.