CHEST®, the flagship journal of the American College of Chest Physicians, was first published in 1935 as Diseases of the Chest, founded, along with the College, by Murray Kornfeld, a patient then recovering from tuberculosis. Dr. Charles Hendricks was elected to be the journal's first Editor in Chief (EIC). In the 1950s, with medications available to quell the spread of TB, the journal expanded its scope to examine other disease states of the chest and lungs. Dr. Alfred Soffer became EIC in 1968 and, in 1970, changed the journal name to CHEST®. Under his editorship, the journal grew in stature and prestige. Dr. A. Jay Block became EIC in 1993, and the journal continued to thrive and grow in to the highest circulation of any respiratory or critical care journal in the world. In 2005, Dr. Richard S. Irwin assumed the helm, developing special sections to serve the broad range of practicing clinicians across pulmonary, critical care, and sleep medicine, while humanizing the patient-physician journey by incorporating humor and the arts. Dr. Irwin’s second term as EIC ends June 30, 2019.